Dissertation (Dr. med. vet.)
Novel appetite stimulants to treat anorexia nervosa and anorexia-cachexia

A position for a doctoral student is available at the Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich. This position will be in collaboration with the biotechnological company EraCal Therapeutics AG in Schlieren.

The candidate will be part of an ambitious research team focusing on the discovering new small molecules to prevent inappetence. Appetite reduction is a hallmark of human disease and most notable in anorexia nervosa and cancer anorexia cachexia patients. The end goal of this project is to develop first-in-class medication to treat common and rare forms of anorexia based on novel mechanisms in stimulating appetite. The experimental work will be performed in Zebrafish larvae to screen and assess the anorectic effect of small molecules. Dose-response, embryologic mortality, developmental defects and/or developmental delays will be determined.

Starting date: September 2021

Duration: approx. 9 months

Salary: according to the guidelines of the Swiss National Science Foundation (CHF 47’540 per year)

Contact for more information:

PD Christelle Le Foll, PhD
Phone: +41 – 44 – 635 88 36
christelle.lefoll@uzh.ch

 

 

Master thesis
Novel appetite stimulants to treat anorexia nervosa and anorexia-cachexia

A position for a master student is available at the Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich. This position will be in collaboration with the biotechnological company EraCal Therapeutics AG in Schlieren.

The candidate will be part of an ambitious research team focusing on the discovering new small molecules to prevent inappetence. Appetite reduction is a hallmark of human disease and most notable in anorexia nervosa and cancer anorexia cachexia patients. The end goal of this project is to develop first-in-class medication to treat common and rare forms of anorexia based on novel mechanisms in stimulating appetite. The experimental work will be performed in Zebrafish larvae to screen and assess the anorectic effect of small molecules. Dose-response, embryologic mortality, developmental defects and/or developmental delays will be determined. He/she will work along with a veterinary dissertation student.

Starting date: September 2021 (flexible)

Contact for more information:

PD Christelle Le Foll, PhD
Phone: +41 – 44 – 635 88 36
christelle.lefoll@uzh.ch